Mefenamic Acid 250mg and Drotaverine 80mg combination is commonly used to treat conditions involving pain and spasms. Mefenamic acid is a nonsteroidal anti-inflammatory drug (NSAID) that helps reduce inflammation, pain, and fever. It is often used for dysmenorrhea (painful menstruation), arthritis, and mild to moderate pain. Drotaverine is an antispasmodic agent that works by relaxing smooth muscles and is effective in treating conditions like abdominal cramps and gastrointestinal spasms. Together, this combination is beneficial for treating menstrual cramps, gastrointestinal spasms, and other pain associated with smooth muscle spasms. Common side effects may include nausea, vomiting, dizziness, or diarrhea, though they are typically mild. This combination should be used under the guidance of a healthcare provider to minimize side effects and ensure efficacy.